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Shire Human Genetic Therapies Inc

48 H-1B petitions, 97.9% certified, $135,498 median salary, FY2023–2026.

Lexington, MA NAICS: 3254

The verdict

Shire Human Genetic Therapies Inc filed 48 H-1B petitions, more than 96% of U.S. sponsors - certified at 97.9% with a $135,498 median offered wage.

48
H-1B petitions, FY2023–FY2026
97.9%
DOL-certified
$135,498
median offered wage
Top 4%
of sponsors by volume

Based in Lexington, MA. Computed live from U.S. Department of Labor LCA disclosures.

H-1B sponsorship profile: Shire Human Genetic Therapies Inc. Across U.S. Department of Labor LCA disclosures, Shire Human Genetic Therapies Inc filed 48 Labor Condition Applications covering 48 H-1B worker positions between fiscal year 2023 and fiscal year 2026. The employer’s DOL certification rate sits at 97.9% (47 certified of 48 filed), a useful proxy for how cleanly their prevailing-wage attestations pass the Labor Department’s preliminary review before USCIS adjudication.

Compensation spread. Offered wages on Shire Human Genetic Therapies Inc’s H-1B petitions range from $75,000 at the low end to $225,000 at the high end, with a petition-weighted average of $135,498. That range reflects the mix of occupations the company sponsors, led by Senior Validation Engineer (4 petitions at $118,563 avg), followed by Validation Manager and Team Lead, Global Reg Affairs Device, PDT. H-1B salaries reported on LCAs must meet or exceed the DOL prevailing wage for the role and worksite, so the spread also tracks wage-level geography and seniority.

Geographic footprint. Shire Human Genetic Therapies Inc is headquartered in Lexington, MA under NAICS code 3254, and places H-1B workers across 1 state, most heavily in MA. Combined, these signals give a granular view of how one employer uses the H-1B program, volume, approval cleanliness, wage posture, and where the jobs actually sit on the map.

Where Shire Human Genetic Therapies Inc ranks. By H-1B petition volume, Shire Human Genetic Therapies Inc is #4,840 of 119,880 employers nationally and #213 of 5,193 employers headquartered in MA. Both ranks are computed live from the same underlying petition counts, not a separate estimate.

Certification Rate

97.9%

Avg. Salary

$135,498

Median Salary

$135,498

Total Workers

48

Compare with another sponsor

Shire Human Genetic Therapies Inc vs a peer vs the national average, from DOL LCA data.

Avg. offered wage$135,498 · 16% higher than Fidelity Technology Group, LLC
This sponsor
Peer
$116,524
National avg.
$112,482
Certification rate97.9% · 2% lower than Fidelity Technology Group, LLC
This sponsor
Peer
99.4%
National avg.
97.7%
Total petitions48 · 99% lower than Fidelity Technology Group, LLC
This sponsor
Peer
3,808
National avg.
16
Filing Growth (FY2023 to FY2026) 6.0%
Wondering how long it takes USCIS to process an H-1B petition for this employer? See current I-129 processing times →

Salary Analysis

Compensation range for H-1B positions at Shire Human Genetic Therapies Inc

Minimum
$75,000
Maximum
$225,000
Average Salary
$135,498

Wage vs. DOL Minimum

+18.4%

national avg +17.9%

Typical DOL Wage Level

Fully Competent (Level IV)

41.7% of petitions

Full-Time Positions

100%

Primary Worksite County

LEXINGTON, MA

77.1% of petitions

Petition History

H-1B filing trends from FY2023 to FY2026

FY2023 18 petitions · 44.4% certified · $135,466 avg
FY2024 21 petitions · 81% certified · $134,280 avg
FY2025 8 petitions · 75% certified · $134,466 avg

FY2026 is partial data (through Q1). Chart shows completed fiscal years only.

Year Petitions Certified Avg. Salary
FY2023 18 8 $135,466
FY2024 21 17 $134,280
FY2025 8 6 $134,466
FY2026(partial) 1 1 $169,914

Top Occupations

Most frequently sponsored job titles at Shire Human Genetic Therapies Inc

Job Title Petitions Avg. Salary
Senior Validation Engineer 4 $118,563
Validation Manager 3 $159,502
Team Lead, Global Reg Affairs Device, PDT 2 $204,127
Senior Downstream Engineer I 2 $105,183
Scientist 2 $106,012
Regulatory Lead 2 $152,193
Product Quality Lead 2 $195,000
Engineer II 2 $85,850
Digital Analyst 2 $130,000
Validation Engineer II 1 $98,000
Validation Engineer - Process Validation, Professional II 1 $101,706
Team Lead, Device Regulatory Affairs, PDT BU 1 $210,251
Sr. Validation Engineer 1 $130,000
Senior Validation Engineer II 1 $154,166
Senior Reliability Engineer 1 $123,000

Geographic Distribution

Where Shire Human Genetic Therapies Inc places H-1B workers across the United States

MA 48 petitions

Recent LCA Petitions

Latest H-1B labor condition applications filed by Shire Human Genetic Therapies Inc

Job Title Location Salary Status Year
Validation Manager Lexington, MA $169,914 Certified FY2026
Scientist Lexington, MA $106,012 Certified - Withdrawn FY2025
Quality Manager - QA Operations Lexington, MA $147,733 Certified FY2025
Automation Engineer Lexington, MA $93,000 Certified FY2025
Senior Process Validation Engineer I Lexington, MA $109,781 Certified FY2025
Director, Head of Manufacturing Science Downstream Lexington, MA $225,000 Certified FY2025
Senior Manager, Process Engineering Lexington, MA $160,775 Certified FY2025
Senior Validation Engineer Lexington, MA $128,426 Certified FY2025
Senior Development Engineer I - Downstream Lexington, MA $105,000 Certified - Withdrawn FY2025
QC Analyst II Lexington, MA $85,000 Certified FY2024
Project Portfolio Specialist Lexington, MA $126,561 Certified FY2024
Validation Engineer - Process Validation, Professional II Lexington, MA $101,706 Certified FY2024
Senior Engineer II LEXINGTON, MA $138,820 Certified FY2024
CMC Submission Lead Lexington, MA $97,000 Certified FY2024
Scientist Lexington, MA $106,012 Certified FY2024
Team Lead, Device Regulatory Affairs, PDT BU Lexington, MA $210,251 Certified FY2024
Regulatory Lead Cambridge, MA $152,193 Certified FY2024
Senior Validation Engineer II Lexington, MA $154,166 Certified FY2024
Regulatory Lead Cambridge, MA $152,193 Certified FY2024
Director, Quality Risk Management Lexington, MA $197,450 Certified FY2024
Engineer I Cambridge, MA $75,000 Certified - Withdrawn FY2024
Product Quality Lead Lexington, MA $195,000 Certified FY2024
Product Quality Lead Lexington, MA $195,000 Withdrawn FY2024
Digital Analyst Fitchburg, MA $130,000 Certified FY2024
Digital Analyst Lexington, MA $130,000 Certified FY2024
Engineer II Cambridge, MA $85,850 Certified - Withdrawn FY2024
Quality Disposition Manager Lexington, MA $139,252 Certified FY2024
Sr. Validation Engineer Lexington, MA $130,000 Certified FY2024
Validation Engineer II Lexington, MA $98,000 Certified FY2024
QC Scientist Lexington, MA $120,422 Certified - Withdrawn FY2024
Associate Director, CMC Regulatory Submissions Cambridge, MA $179,106 Certified FY2023
Senior Validation Engineer Lexington, MA $120,000 Certified - Withdrawn FY2023
Application Engineer Lexington, MA $149,241 Certified FY2023
Engineer II Cambridge, MA $85,850 Certified FY2023
Quality Control Scientist I Lexington, MA $115,000 Certified FY2023
Quality Control Analyst Lexington, MA $78,814 Certified - Withdrawn FY2023
Senior Engineer Lexington, MA $135,345 Certified - Withdrawn FY2023
Associate Director, Operations Technology Lexington, MA $195,000 Certified - Withdrawn FY2023
Senior Development Engineer Lexington, MA $104,000 Certified - Withdrawn FY2023
Senior Reliability Engineer Lexington, MA $123,000 Certified - Withdrawn FY2023
Validation Manager Lexington, MA $154,295 Certified FY2023
Senior Downstream Engineer I Lexington, MA $105,183 Certified - Withdrawn FY2023
Senior Validation Engineer Lexington, MA $112,913 Certified - Withdrawn FY2023
Team Lead, Global Reg Affairs Device, PDT Lexington, MA $204,127 Certified FY2023
Validation Manager Lexington, MA $154,295 Certified FY2023
Team Lead, Global Reg Affairs Device, PDT Lexington, MA $204,127 Certified FY2023
Senior Downstream Engineer I Lexington, MA $105,183 Certified - Withdrawn FY2023
Senior Validation Engineer Lexington, MA $112,913 Certified - Withdrawn FY2023

Similar Employers in MA

Other H-1B sponsors based in MA, ranked by petition volume

Compare Shire Human Genetic Therapies Inc vs Fidelity Technology Group, LLC side-by-side →

Frequently Asked Questions

How many H-1B petitions has Shire Human Genetic Therapies Inc filed?

Shire Human Genetic Therapies Inc has filed 48 H-1B LCA petitions covering 48 worker positions from FY2023 to FY2026.

What is the H-1B approval rate for Shire Human Genetic Therapies Inc?

Shire Human Genetic Therapies Inc has a 97.9% certification rate, with 47 out of 48 petitions certified.

What is the average H-1B salary at Shire Human Genetic Therapies Inc?

The average H-1B salary at Shire Human Genetic Therapies Inc is $135,498. Salaries range from $75,000 to $225,000.

What are the most common H-1B job titles at Shire Human Genetic Therapies Inc?

The top H-1B job titles at Shire Human Genetic Therapies Inc include Senior Validation Engineer, Validation Manager, Team Lead, Global Reg Affairs Device, PDT. The most common position is Senior Validation Engineer with 4 petitions at an average salary of $118,563.

Where is Shire Human Genetic Therapies Inc located?

Shire Human Genetic Therapies Inc is headquartered in Lexington, MA.

Is Shire Human Genetic Therapies Inc H-1B dependent?

No, Shire Human Genetic Therapies Inc is not classified as H-1B dependent.

How has Shire Human Genetic Therapies Inc's H-1B sponsorship changed over time?

Shire Human Genetic Therapies Inc filed 18 petitions in FY2023 and 1 in FY2026. Average salary increased from $135,466 to $169,914.

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Data Sources

H-1B visa petition data is sourced from the U.S. Department of Labor (DOL) Labor Condition Application (LCA) disclosure files. Data covers fiscal years 2023 through 2026. Salary figures reflect amounts listed on LCA petitions, not actual compensation paid. Certification of an LCA does not guarantee visa approval.

Source: DOL Foreign Labor Performance Data

Source: U.S. Department of Labor, Office of Foreign Labor Certification, LCA Disclosure Data (FY2023–FY2026)

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from the U.S. Department of Labor LCA disclosure files. Consult a qualified professional before making decisions based on this data.

Every figure on PlainVisa is rendered directly from federal source data, no number is typed in by an editor. This page draws directly on federal source data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.