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2026 data Public-data reference Official source

Denali Therapeutics Inc

43 H-1B petitions, 93% certified, $154,694 median salary, FY2023–2026.

South San Francisco, CA NAICS: 325412

The verdict

Denali Therapeutics Inc filed 43 H-1B petitions, more than 96% of U.S. sponsors - certified at 93% with a $154,694 median offered wage.

43
H-1B petitions, FY2023–FY2026
93%
DOL-certified
$154,694
median offered wage
Top 4%
of sponsors by volume

Based in South San Francisco, CA. Computed live from U.S. Department of Labor LCA disclosures.

H-1B sponsorship profile: Denali Therapeutics Inc. Across U.S. Department of Labor LCA disclosures, Denali Therapeutics Inc filed 43 Labor Condition Applications covering 43 H-1B worker positions between fiscal year 2023 and fiscal year 2026. The employer’s DOL certification rate sits at 93% (40 certified of 43 filed), a useful proxy for how cleanly their prevailing-wage attestations pass the Labor Department’s preliminary review before USCIS adjudication.

Compensation spread. Offered wages on Denali Therapeutics Inc’s H-1B petitions range from $75,000 at the low end to $265,000 at the high end, with a petition-weighted average of $154,694. That range reflects the mix of occupations the company sponsors, led by Scientist (6 petitions at $148,219 avg), followed by Senior Scientist, Large Molecule Formulation Development and Director, Clinical Operations. H-1B salaries reported on LCAs must meet or exceed the DOL prevailing wage for the role and worksite, so the spread also tracks wage-level geography and seniority.

Geographic footprint. Denali Therapeutics Inc is headquartered in South San Francisco, CA under NAICS code 325412, and places H-1B workers across 3 states, most heavily in CA, UT, NC. Combined, these signals give a granular view of how one employer uses the H-1B program, volume, approval cleanliness, wage posture, and where the jobs actually sit on the map.

Where Denali Therapeutics Inc ranks. By H-1B petition volume, Denali Therapeutics Inc is #5,367 of 119,880 employers nationally and #781 of 22,893 employers headquartered in CA. Both ranks are computed live from the same underlying petition counts, not a separate estimate.

Certification Rate

93%

Avg. Salary

$154,694

Median Salary

$154,694

Total Workers

43

Compare with another sponsor

Denali Therapeutics Inc vs a peer vs the national average, from DOL LCA data.

Avg. offered wage$154,694 · 13% lower than Google LLC
This sponsor
Peer
$178,734
National avg.
$112,482
Certification rate93.0% · 5% lower than Google LLC
This sponsor
Peer
98.4%
National avg.
97.7%
Total petitions43 · 100% lower than Google LLC
This sponsor
Peer
30,573
National avg.
16
Filing Growth (FY2023 to FY2026) 42.0%
Wondering how long it takes USCIS to process an H-1B petition for this employer? See current I-129 processing times →

Salary Analysis

Compensation range for H-1B positions at Denali Therapeutics Inc

Minimum
$75,000
Maximum
$265,000
Average Salary
$154,694

Wage vs. DOL Minimum

+15.1%

national avg +17.9%

Typical DOL Wage Level

Qualified (Level II)

41.9% of petitions

Full-Time Positions

100%

Primary Worksite County

SAN MATEO, CA

83.7% of petitions

Petition History

H-1B filing trends from FY2023 to FY2026

FY2023 12 petitions · 66.7% certified · $157,483 avg
FY2024 15 petitions · 46.7% certified · $149,056 avg
FY2025 11 petitions · 81.8% certified · $163,927 avg

FY2026 is partial data (through Q1). Chart shows completed fiscal years only.

Year Petitions Certified Avg. Salary
FY2023 12 8 $157,483
FY2024 15 7 $149,056
FY2025 11 9 $163,927
FY2026(partial) 5 4 $144,600

Top Occupations

Most frequently sponsored job titles at Denali Therapeutics Inc

Job Title Petitions Avg. Salary
Scientist 6 $148,219
Senior Scientist, Large Molecule Formulation Development 3 $140,667
Director, Clinical Operations 3 $221,000
Senior Engineer, Cybersecurity 2 $160,221
Scientist, Discovery Pharmacology 2 $123,259
Medical Director, Global Drug Safety 2 $265,000
Clinical Data Manager 2 $179,878
Associate Data Engineer 2 $119,500
Senior Scientist, Tech Op 1 $152,041
Senior Scientist, Discovery Biology 1 $142,000
Senior Scientist, Data 1 $158,000
Senior Scientist, Cell Process Development 1 $138,000
Senior Manufacturing Sciences and Technology Engineer 1 $130,000
Senior Manager, Cybersecurity 1 $167,000
Scientist, iPSC Discovery Biology 1 $121,000

Geographic Distribution

Where Denali Therapeutics Inc places H-1B workers across the United States

CA 40 petitions
UT 2 petitions
NC 1 petitions

Recent LCA Petitions

Latest H-1B labor condition applications filed by Denali Therapeutics Inc

Job Title Location Salary Status Year
Quality Assurance Specialist Salt Lake City, UT $100,000 Certified FY2026
Senior Manager, Cybersecurity South San Francisco, CA $167,000 Certified FY2026
Senior Scientist, Cell Process Development South San Francisco, CA $138,000 Certified FY2026
Senior Scientist, Large Molecule Formulation Development South San Francisco, CA $138,000 Certified FY2026
Senior Engineer, Cybersecurity South San Francisco, CA $180,000 Withdrawn FY2026
Associate Director, Clinical Data Management Holly Springs, NC $204,194 Certified FY2025
Senior Scientist, Data South San Francisco, CA $158,000 Certified FY2025
Scientist, iPSC Discovery Biology South San Francisco, CA $121,000 Certified FY2025
Director, Clinical Operations South San Francisco, CA $209,000 Certified FY2025
Scientist, Discovery Pharmacology South San Francisco, CA $123,000 Certified FY2025
Principal Scientist, Translational Medicine South San Francisco, CA $165,333 Certified FY2025
Senior Scientist, Discovery Biology South San Francisco, CA $142,000 Certified FY2025
Associate Scientist, Discovery Pharmacology South San Francisco, CA $122,166 Certified FY2025
Associate Director, Enterprise Data Architect South San Francisco, CA $174,000 Certified FY2025
Medical Director, Global Drug Safety South San Francisco, CA $265,000 Certified - Withdrawn FY2025
Associate Data Engineer South San Francisco, CA $119,500 Certified - Withdrawn FY2025
Senior Scientist, Large Molecule Formulation Development South San Francisco, CA $142,000 Certified FY2024
Senior Scientist, Large Molecule Formulation Development South San Francisco, CA $142,000 Withdrawn FY2024
Medical Director, Global Drug Safety South San Francisco, CA $265,000 Certified FY2024
Scientist, Bioanalysis South San Francisco, CA $128,939 Certified FY2024
Senior Manufacturing Sciences and Technology Engineer Salt Lake City, UT $130,000 Certified FY2024
Scientist, Protein Purification and Characterization South San Francisco, CA $109,438 Certified - Withdrawn FY2024
Scientist, Quantitative Pharmacology South San Francisco, CA $140,000 Certified FY2024
Associate Scientist, In Vivo South San Francisco, CA $101,816 Certified FY2024
Scientist South San Francisco, CA $202,563 Certified - Withdrawn FY2024
Director, Learning & Organizational Development South San Francisco, CA $220,000 Certified - Withdrawn FY2024
Scientist South San Francisco, CA $109,438 Certified - Withdrawn FY2024
Scientist South San Francisco, CA $123,000 Certified - Withdrawn FY2024
Program Director South San Francisco, CA $223,034 Certified FY2024
Scientist, Protein Mass Spect. & Analytical Development South San Francisco, CA $123,614 Certified - Withdrawn FY2024
Postdoctoral Scientist South San Francisco, CA $75,000 Certified - Withdrawn FY2024
Associate Data Engineer South San Francisco, CA $119,500 Certified FY2023
Scientist South San Francisco, CA $202,563 Withdrawn FY2023
Research Scientist South San Francisco, CA $86,220 Certified - Withdrawn FY2023
Senior Scientist, Tech Op South San Francisco, CA $152,041 Certified FY2023
Scientist South San Francisco, CA $128,752 Certified - Withdrawn FY2023
Scientist South San Francisco, CA $123,000 Certified FY2023
Scientist, Discovery Pharmacology South San Francisco, CA $123,518 Certified - Withdrawn FY2023
Senior Engineer, Cybersecurity South San Francisco, CA $140,442 Certified FY2023
Clinical Data Manager South San Francisco, CA $179,878 Certified FY2023
Director, Clinical Operations South San Francisco, CA $227,000 Certified FY2023
Clinical Data Manager South San Francisco, CA $179,878 Certified FY2023
Director, Clinical Operations South San Francisco, CA $227,000 Certified FY2023

Similar Employers in CA

Other H-1B sponsors based in CA, ranked by petition volume

Compare Denali Therapeutics Inc vs Google LLC side-by-side →

Frequently Asked Questions

How many H-1B petitions has Denali Therapeutics Inc filed?

Denali Therapeutics Inc has filed 43 H-1B LCA petitions covering 43 worker positions from FY2023 to FY2026.

What is the H-1B approval rate for Denali Therapeutics Inc?

Denali Therapeutics Inc has a 93% certification rate, with 40 out of 43 petitions certified.

What is the average H-1B salary at Denali Therapeutics Inc?

The average H-1B salary at Denali Therapeutics Inc is $154,694. Salaries range from $75,000 to $265,000.

What are the most common H-1B job titles at Denali Therapeutics Inc?

The top H-1B job titles at Denali Therapeutics Inc include Scientist, Senior Scientist, Large Molecule Formulation Development, Director, Clinical Operations. The most common position is Scientist with 6 petitions at an average salary of $148,219.

Where is Denali Therapeutics Inc located?

Denali Therapeutics Inc is headquartered in South San Francisco, CA. Their H-1B workers are distributed across 3 states, with the most positions in CA, UT, NC.

Is Denali Therapeutics Inc H-1B dependent?

No, Denali Therapeutics Inc is not classified as H-1B dependent.

How has Denali Therapeutics Inc's H-1B sponsorship changed over time?

Denali Therapeutics Inc filed 12 petitions in FY2023 and 5 in FY2026. Average salary changed from $157,483 to $144,600.

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Data Sources

H-1B visa petition data is sourced from the U.S. Department of Labor (DOL) Labor Condition Application (LCA) disclosure files. Data covers fiscal years 2023 through 2026. Salary figures reflect amounts listed on LCA petitions, not actual compensation paid. Certification of an LCA does not guarantee visa approval.

Source: DOL Foreign Labor Performance Data

Source: U.S. Department of Labor, Office of Foreign Labor Certification, LCA Disclosure Data (FY2023–FY2026)

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from the U.S. Department of Labor LCA disclosure files. Consult a qualified professional before making decisions based on this data.

Every figure on PlainVisa is rendered directly from federal source data, no number is typed in by an editor. This page draws directly on federal source data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.